Formulation Proposal

We design the optimum solvent you desire by using the solubility value (Hansen Solubility Parameters), which is an index of the affinity between substances.We propose a formulation to change from a highly hazardous solvent to an environment-friendly blended solvent based on the idea that "those with similar HSP values are compatible," keeping in mind what solvent the polymer dissolves in, how stable various additives can exist, etc.

Cleaning, dissolving, legal compliance, etc....
Andoh Parachemie will solve your worries!
Solvent Development Using HSP Value

Materials with similar three intermolecular energies bond well

  • ΔD:Dispersion energy between molecules
    ΔP: Dipole interaction energy between molecules
    ΔH:Intramolecular hydrogen bond energy
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  • Three parameters are shown in 3D space
    and each property is predicted by each positional relationship.
    Good solubility if the spatial coordinates of different substances are close to one another.
  HSP
HSP value of typical solvent(Unit:MPa½ )
Solvent ΔD ΔP ΔH
n-Hexane 15.3 0 0
Tetrahydrofuran 16.8 5.7 8.0
Ethanol 15.8 8.8 19.4
N,N-dimethylformamide(DMF) 17.4 13.7 11.3

Adjustment of blend solvent to acquire targeted physical properties (solubility, polarity) is
possible by controlling the HSP Value by combining various raw materials handled
by Andoh Parachemie!


We will undertake contract examination and development, so please make good use of us!


  • ◆Modification of existing solvents to comply with current regulations, consideration of development of alternative solvents
  • ◆Examination of development of optimum solvent for soluble substances such as polymers and chemicals
  • ◆Solvent cleaning for specific stains
 

Flow of Formulation Proposal

  1. 1

    Understanding requests

    Please fill in the Blended Solvent Proposal Check Sheet
  2. 2

    Examination of blending solvent

    Consider a compounding solvent that meets your needs based on the HSP value
  3. 3

    Proposal

    We propose compounding solvent that meets your needs
  4. 4

    Sample Offer

    We will offer samples of the compounding solvent
  5. 5

    Sale

    Create specifications and start selling the compounded solvents

Use of HSP value is not limited to application to alternative solvents.Below are some examples of other ideas

  • Liquid and liquid, solid and liquid, gas and liquid
  • Affinity between inorganic and organic, biological and organic substances (wetness, etc.)
  • Solubility of polymer and solvent

Application example

High resilience agent for golf balls, eye drops that will be absorbed well by the eyes, dispersion of silica particles, antioxidation of solvents, etc.

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